The study of the photokilling effect and mechanism of ultrafine TiO2 particles on U937 cells
- 15 August 1997
- journal article
- Published by Elsevier BV in Journal of Photochemistry and Photobiology A: Chemistry
- Vol. 108 (2-3), 229-233
- https://doi.org/10.1016/s1010-6030(97)00093-2
Abstract
The killing effect of photoexcited ultrafine TiO2 particles (UFP TiO2) on U937 cells has been studied. The mechanism concerned has been further investigated by DNA agarose gel electrophoresis. The electrophorogram shows that reactive oxygen species produced by photoexcited UFP TiO2 can damage DNA, which results in cell death. Finally, a new assumption of the way to kill cancer cells is proposed.Keywords
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