Phylogenetic analysis of Chinese sheeppox and goatpox virus isolates
Open Access
- 20 January 2012
- journal article
- Published by Springer Science and Business Media LLC in Virology Journal
- Vol. 9 (1), 25
- https://doi.org/10.1186/1743-422x-9-25
Abstract
Background: Sheeppox virus (SPPV) and goatpox virus (GTPV), members of the Capripoxvirus genus of the Poxviridae family are causative agents of sheep pox and goat pox respectively, which are important contagious diseases and endemic in central and northern Africa, the Middle and Far East, and the Indian sub-continent. Both sheep pox and goat pox can cause wool and hide damage, and reduce the production of mutton and milk, which may result in significant economic losses and threaten the stockbreeding. In this study, three SPPVs and two GTPVs were collected from China in 2009 and 2011. We described the sequence features and phylogenetic analysis of the P32 gene, GPCR gene and RPO30 gene of the SPPVs and GTPVs to reveal their genetic relatedness. Results: Sequence and phylogenetic analysis showed that there was a close relationship among SPPV/GanS/2/2011/China, SPPV/GanS/1/2011/China and SPPV/NingX/2009/China. They were clustered on the same SPPV clade. GTPV/HuB/2009/China and GS-V1 belonged to the GTPV lineage. GS-V1 was closely related to other GTPV vaccine strains. GTPV/HuB/2009/China and GS-V1 were clustered with GTPVs from China and some southern Asian countries. Conclusion: This study may expand the datum for spread trend research of Chinese SPPVs and GTPVs, meanwhile provide theoretical references to improve the preventive and control strategy.Keywords
This publication has 15 references indexed in Scilit:
- Emerging Capripoxvirus Disease Outbreaks in Himachal Pradesh, a Northern State of IndiaTransboundary and Emerging Diseases, 2010
- Pox outbreaks in Sheep and Goats at Makhdoom (Uttar Pradesh), India: Evidence of Sheeppox Virus Infection in GoatsTransboundary and Emerging Diseases, 2010
- Capripoxvirus G-protein-coupled chemokine receptor: a host-range gene suitable for virus animal origin discriminationJournal of General Virology, 2009
- Capripoxviruses: An Emerging Worldwide Threat to Sheep, Goats and CattleTransboundary and Emerging Diseases, 2008
- MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0Molecular Biology and Evolution, 2007
- Genus CapripoxvirusPublished by Springer Science and Business Media LLC ,2007
- The current status of sheep pox diseaseComparative Immunology, Microbiology and Infectious Diseases, 2006
- Sequence Analysis of HindIII Q2 Fragment of Capripoxvirus Reveals a Putative Gene Encoding a G-Protein-Coupled Chemokine Receptor HomologueVirology, 1995
- A comparison of the genomes of capripoxvirus isolates of sheep, goats, and cattleVirology, 1988
- Confidence Limits on Phylogenies: An Approach Using the BootstrapEvolution, 1985