Mitochondrial Genetics: A Paradigm for Aging and Degenerative Diseases?
- 1 May 1992
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 256 (5057), 628-632
- https://doi.org/10.1126/science.1533953
Abstract
Studies of diseases caused by mitochondrial DNA mutations suggest that a variety of degenerative processes may be associated with defects in oxidative phosphorylation (OXPHOS). Application of this hypothesis has provided new insights into such diverse clinical problems as ischemic heart disease, late-onset diabetes, Parkinson's disease, Alzheimer's disease, and aging.This publication has 65 references indexed in Scilit:
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