Motor Nerve Sprouting and Acetylcholine Receptors
- 17 March 1978
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 199 (4334), 1223-1225
- https://doi.org/10.1126/science.204007
Abstract
Sprouting of motor nerve terminals was evoked by functional denervation of skeletal muscles brought about by presynaptic blockade or disuse. The amount of sprouting, determined by morphometric measurement, was correlated with the level of extrajunctional acetylcholine receptors. Sprouting was inhibited by blockade of acetylcholine receptors with alpha-bungarotoxin. Extrajunctional acetylcholine receptors may play an important role in eliciting motor nerve terminal sprouting.This publication has 25 references indexed in Scilit:
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