DNA Strand Breakage in Human Leukocytes Exposed to a Tumor Promoter, Phorbol Myristate Acetate
- 5 March 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 215 (4537), 1247-1249
- https://doi.org/10.1126/science.6276978
Abstract
The phorbol myristate acetate-stimulated respiratory burst in human peripheral blood leukocytes is associated with extensive DNA strand breakage. Damage to DNA oocurs before gross cellular damage is evident and may be related to the action of phorbol myristate acetate as a skin tumor promoter in animals.This publication has 13 references indexed in Scilit:
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