Some Properties of a New Bacteriocin Formed by Bacillus megaterium
- 1 May 1964
- journal article
- research article
- Published by Microbiology Society in Journal of General Microbiology
- Vol. 35 (2), 271-285
- https://doi.org/10.1099/00221287-35-2-271
Abstract
Summary: A new bacteriocin, megacin C, was recognized in certain strains of Bacillus megaterium; it was initially observed as the agent responsible for killing sensitive organisms in mixed culture. The bacteriocin was liberated during growth of cultures; but later, after reaching a maximum value, it disappeared from the culture media. Megacin C was produced by strains already known to produce another bacteriocin, megacin A. The activity spectra of the two megacins differed markedly and non-megacin A (MA -) mutants still produced megacin C. A preliminary grouping of megacin types is proposed. Megacin A is comparable to the original megacin first studied by Ivánovics & Alföldi (1954). Megacin A produced inhibition zones surrounding colonies on solid medium but its formation in liquid medium required induction with ultraviolet (u.v.) radiation. Megacin B, whose activity spectra differed from those of megacins A and C, can be detected only on a solid medium; it is not formed in liquid culture even after u.v.-irradiation. Megacin C can be detected only on a particular solid medium and its formation in liquid media is not induced by u.v.-irradiation.Keywords
This publication has 9 references indexed in Scilit:
- Colicine ANature, 1963
- ETUDE DU POUVOIR BACTERIOCINOGENE DANS LE GENRE LISTERIA .2. INDIVIDUALITE ET CLASSIFICATION DES BACTERIOCINES EN CAUSE1963
- BACTERIOCINS AND BACTERIOCIN-LIKE SUBSTANCESMicrobiology and Molecular Biology Reviews, 1962
- The purification and properties of megacin, a bacteriocin from Bacillus megateriumBiochemical Journal, 1961
- Mode of Action of MegacinJournal of General Microbiology, 1959
- Hereditary Aberrancy in Growth of Some Bacillus megaterium StrainsJournal of General Microbiology, 1958
- COLICINE KThe Journal of Experimental Medicine, 1958
- Bacteriocinogenesis in Bacillus megateriumJournal of General Microbiology, 1957
- UBER EIN COLICIN AUS ESCHERICHIA-COLI SG-7101957