Activation of cytotoxic T lymphocytes in HLA‐A, ‐B and ‐C‐identical responder‐stimulator pairs II
- 1 August 1984
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 24 (2), 90-97
- https://doi.org/10.1111/j.1399-0039.1984.tb02111.x
Abstract
Five cytotoxic T lymphocytes (CTL) raised by primary mixed lymphocyte cultures of HLA-A, -B and -C serologically identical Bw35-positive responder-stimulator combinations were compared. When tested on a panel of 3rd-party target cells, the reactivity pattern of these CTL allowed the distinction of 3 subtypes of HLA-Bw35. Cold-target inhibition experiments and analysis of CTL activity at the clonal level showed the existence of subsets of CTL directed against distinct antigenic determinants associated with HLA-Bw35.This publication has 18 references indexed in Scilit:
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