Digital optical phase conjugation of fluorescence in turbid tissue
Open Access
- 20 August 2012
- journal article
- research article
- Published by AIP Publishing in Applied Physics Letters
- Vol. 101 (8), 081108
- https://doi.org/10.1063/1.4745775
Abstract
We demonstrate a method for phase conjugating fluorescence. Our method, called reference free digital optical phase conjugation, can conjugate extremely weak, incoherent optical signals. It was used to phase conjugate fluorescent light originating from a bead covered with 0.5 mm of light-scattering tissue. The phase conjugated beam refocuses onto the bead and causes a local increase of over two orders of magnitude in the light intensity. Potential applications are in imaging, optical trapping, and targeted photochemical activation inside turbid tissue.Keywords
Funding Information
- "National Institutes of Health" (1DP2OD007307-01)
This publication has 71 references indexed in Scilit:
- Reflection-mode time-reversed ultrasonically encoded optical focusing into turbid mediaJournal of Biomedical Optics, 2011
- Differential Gene Expression in the Pig Limbal Side Population: Implications for Stem Cell Cycling, Replication, and SurvivalInvestigative Opthalmology & Visual Science, 2009
- Epidermal homeostasis: a balancing act of stem cells in the skinNature Reviews Molecular Cell Biology, 2009
- Transcriptional profiling of putative human epithelial stem cellsBMC Genomics, 2008
- Adult stem cell maintenance and tissue regeneration in the ageing context: the role for A‐type lamins as intrinsic modulators of ageing in adult stem cells and their nichesJournal of Anatomy, 2008
- Optical phase conjugation for turbidity suppression in biological samplesNature Photonics, 2008
- Comparative Analysis of Human Conjunctival and Corneal Epithelial Gene Expression with Oligonucleotide MicroarraysPublished by Association for Research in Vision and Ophthalmology (ARVO) ,2007
- Morphological characteristics of the limbal epithelial cryptBritish Journal of Ophthalmology, 2006
- Molecular Signatures of Proliferation and Quiescence in Hematopoietic Stem CellsPLoS Biology, 2004
- Unique gene expression signatures of independently-derived human embryonic stem cell linesHuman Molecular Genetics, 2004