Mortality and causes of death in autism spectrum disorders
- 1 July 2008
- journal article
- Published by SAGE Publications in Autism
- Vol. 12 (4), 403-414
- https://doi.org/10.1177/1362361308091653
Abstract
This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960—93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths.This publication has 17 references indexed in Scilit:
- Autism after Adolescence: Population-based 13- to 22-year Follow-up Study of 120 Individuals with Autism Diagnosed in ChildhoodJournal of Autism and Developmental Disorders, 2005
- Outcomes in Autism Spectrum DisordersPublished by Wiley ,2005
- Adult outcome for children with autismJournal of Child Psychology and Psychiatry, 2004
- SUDEP: Overview of definitions and review of incidence dataSeizure, 1999
- Mortality and Causes of Death in Pervasive Developmental DisordersAutism, 1999
- A clinicopathological study of autismBrain, 1998
- The outcome in children with childhood autism and Asperger syndrome originally diagnosed as psychotic. A 30-year follow-up study of subjects hospitalized as childrenEuropean Child & Adolescent Psychiatry, 1997
- Longitudinal examination of the behavioral, language, and social changes in a population of adolescents and young adults with autistic disorderPediatric Neurology, 1996
- A follow-up study of 201 children with autism in Kyushu and Yamaguchi areas, JapanJournal of Autism and Developmental Disorders, 1992
- Excess Mortality Among Formerly Hospitalized Child Psychiatric PatientsArchives of General Psychiatry, 1988