The characteristics of side‐effects of bromperidol in schizophrenic patients
Open Access
- 21 January 2002
- journal article
- Published by Wiley in Psychiatry and Clinical Neurosciences
- Vol. 56 (1), 103-106
- https://doi.org/10.1046/j.1440-1819.2002.00936.x
Abstract
The characteristics of the side‐effects of bromperidol was investigated in 33 acutely exacerbated schizophrenic patients. The most frequently observed side‐effects were extrapyramidal symptoms. Acute dystonia developed in 10 of 33 patients, and the mean age was significantly lower (P < 0.05) in patients with dystonia (27.3 ± 6.2 years) than that in patients without dystonia (41.5 ± 12.9 years). Plasma drug concentrations were not associated with side‐effects. These findings suggest that acute dystonia is affected by age factor, and that daily dosage or monitoring of drug concentration is unlikely to be a useful marker for the prediction of side‐effects during bromperidol treatment.Keywords
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