Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
Open Access
- 9 February 2022
- journal article
- research article
- Published by Elsevier BV in Cell
- Vol. 185 (5), 896-915.e19
- https://doi.org/10.1016/j.cell.2022.02.005
Abstract
No abstract availableKeywords
This publication has 80 references indexed in Scilit:
- Airway Memory CD4 + T Cells Mediate Protective Immunity against Emerging Respiratory CoronavirusesImmunity, 2016
- Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protectionMucosal Immunology, 2015
- Mucosal immunity and novel tuberculosis vaccine strategies: route of immunisation-determined T-cell homing to restricted lung mucosal compartmentsEuropean Respiratory Review, 2015
- Safety and immunogenicity of a candidate tuberculosis vaccine MVA85A delivered by aerosol in BCG-vaccinated healthy adults: a phase 1, double-blind, randomised controlled trialThe Lancet Infectious Diseases, 2014
- Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus InfectionPLoS Pathogens, 2014
- Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigenThe Journal of Experimental Medicine, 2012
- What Role Does the Route of Immunization Play in the Generation of Protective Immunity against Mucosal Pathogens?The Journal of Immunology, 2009
- Alveolar Macrophages Are the Primary Interferon-α Producer in Pulmonary Infection with RNA VirusesImmunity, 2007
- Exosomal vaccines containing the S protein of the SARS coronavirus induce high levels of neutralizing antibodiesVirology, 2007
- Mucosal vaccines: the promise and the challengeNature Reviews Immunology, 2006