In Vivo Manipulation of the Bleomycin Biosynthetic Gene Cluster in Streptomyces verticillus ATCC15003 Revealing New Insights into Its Biosynthetic Pathway
Open Access
- 17 October 2008
- journal article
- Published by Elsevier BV
- Vol. 283 (42), 28236-28245
- https://doi.org/10.1074/jbc.m804971200
Abstract
No abstract availableThis publication has 38 references indexed in Scilit:
- Crystal structure of DNA-bound Co(III)·bleomycin B 2 : Insights on intercalation and minor groove bindingProceedings of the National Academy of Sciences of the United States of America, 2008
- Glycopeptide Antitumor Antibiotic Zorbamycin from Streptomyces flavoviridis ATCC 21892: Strain Improvement and Structure ElucidationJournal of Natural Products, 2007
- The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibioticsMolecular BioSystems, 2006
- In Vivo Analysis of the Regulatory Genes in the Nystatin Biosynthetic Gene Cluster of Streptomyces noursei ATCC 11455 Reveals Their Differential Control Over Antibiotic BiosynthesisJournal of Bacteriology, 2004
- Characterization of NovP and NovN: Completion of Novobiocin Biosynthesis by Sequential Tailoring of the Noviosyl RingAngewandte Chemie-International Edition, 2003
- Integration Site forStreptomycesPhage φBT1 and Development of Site-Specific Integrating VectorsJournal of Bacteriology, 2003
- Cloning and Characterization of the Bleomycin Biosynthetic Gene Cluster from Streptomyces verticillus ATCC15003Journal of Natural Products, 2002
- Identification and characterization of a type II peptidyl carrier protein from the bleomycin producer Streptomyces verticillus ATCC 15003Cell Chemical Biology, 1999
- A New Arrangement for the Anticancer Antibiotics Tallysomycin and Bleomycin When Bound to Zinc: An Assessment of Metal and Ligand Chirality by NMR and Molecular DynamicsJournal of the American Chemical Society, 1997
- Gene organization in the bleomycin-resistance region of the producer organism Streptomyces verticillusGene, 1994