Cardiomyopathy of Overload
- 11 January 1990
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 322 (2), 100-110
- https://doi.org/10.1056/nejm199001113220206
Abstract
MORE than 80 years ago, Sir James MacKenzie1 noted: "The more I study the symptoms of heart failure, and the more I reflect on the part played by the heart muscle, the more convinced I am that... heart failure is due to the exhaustion of the reserve force of the heart muscle." Except for the cardiac glycosides, however, therapy for congestive heart failure generally has focused on the systemic signs and symptoms that appear when the failing heart becomes unable to meet the hemodynamic demands of the body, rather than on abnormalities in the heart muscle itself, which both cause . . .Keywords
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