Severe Generalized Bullous Fixed Drug Eruption Treated with Cyclosporine: A Case Report and Literature Review
Open Access
- 3 March 2021
- journal article
- review article
- Published by S. Karger AG in Case Reports in Dermatology
- Vol. 13 (1), 154-163
- https://doi.org/10.1159/000513469
Abstract
Generalized bullous fixed drug eruptions (GBFDEs) are rare in the paediatric population. We present the case of a 7-year-old girl with GBFDE believed to be secondary to oral ibuprofen, who experienced rapid resolution of lesions and cessation of blistering with a 3-week course of oral cyclosporine. To the best of our knowledge, this is the first report of a paediatric case of GBFDE treated with cyclosporine. In our report, we review published cases of GBFDE in children, and all adult cases managed with cyclosporine.Keywords
This publication has 22 references indexed in Scilit:
- Fixed drug eruption: pathogenesis and diagnostic testsCurrent Opinion in Allergy and Clinical Immunology, 2009
- Cutaneous Reactions to Drugs in ChildrenPEDIATRICS, 2007
- BULLOUS NECROTIZING FIXED DRUG ERUPTION IN AN INFANTPediatric Dermatology, 2004
- Antibiotic Rashes in ChildrenArchives of Dermatology, 2000
- Skin Reactions to Antibacterial Agents in General PracticeJournal of Clinical Epidemiology, 1998
- Clinical Pattern of Cutaneous Drug Eruption among Children and Adolescents inPediatric Dermatology, 1995
- Fixed drug eruption: Bullous formClinics in Dermatology, 1993
- Intensive monitoring of adverse drug reactions in infants and preschool childrenEuropean Journal of Clinical Pharmacology, 1989
- Fixed Drug Eruptions in Children: A Series of 23 Cases with Provocative TestsDermatology, 1986
- Adverse drug reactions in general pediatric outpatientsThe Journal of Pediatrics, 1985