Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
- 14 September 2010
- journal article
- editorial
- Published by Elsevier BV in Cancer Cell
- Vol. 18 (3), 207-219
- https://doi.org/10.1016/j.ccr.2010.08.009
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant functionProceedings of the National Academy of Sciences of the United States of America, 2010
- Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen speciesProceedings of the National Academy of Sciences of the United States of America, 2010
- Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progressionProceedings of the National Academy of Sciences of the United States of America, 2010
- Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor GrowthScience Signaling, 2009
- RETRACTED: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer MetastasisCell, 2009
- c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolismNature, 2009
- DLC1: a significant GAP in the cancer genomeJournal of Bone and Joint Surgery, 2008
- DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinomaPublished by Cold Spring Harbor Laboratory ,2008
- Rho GTPases in cancer cell biologyFEBS Letters, 2008
- Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesisProceedings of the National Academy of Sciences of the United States of America, 2007