Potential Secondary Pathogenic Role for Bovine Herpesvirus 4
Open Access
- 1 July 2005
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 43 (7), 3421-3426
- https://doi.org/10.1128/jcm.43.7.3421-3426.2005
Abstract
Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus with no clear disease association. Previous studies have demonstrated that macrophages can harbor persistent BoHV-4. We found that the addition of prostaglandin E2 (PGE2) to bovine macrophage cells persistently infected with BoHV-4 increases viral replication. Because opportunistic infection can increase PGE2 production, we propose a link between opportunistic infection, PGE2 production, and BoHV-4 replication.Keywords
This publication has 19 references indexed in Scilit:
- COX-2 Induction during Murine Gammaherpesvirus 68 Infection Leads to Enhancement of Viral Gene ExpressionJournal of Virology, 2003
- Inhibition of cyclooxygenase 2 blocks human cytomegalovirus replicationProceedings of the National Academy of Sciences, 2002
- Gestational age-dependent effects of lipopolysaccharide on prostaglandin production by murine decidual capsProstaglandins, Leukotrienes & Essential Fatty Acids, 2001
- Immortalization and characterization of bovine peritoneal macrophages transfected with SV40 plasmid DNAVeterinary Immunology and Immunopathology, 1995
- Bacterial lipopolysaccharide-mediated fetal death. Production of a newly recognized form of inducible cyclooxygenase (COX-2) in murine decidua in response to lipopolysaccharide.JCI Insight, 1995
- Biological and biochemical comparison of bovid herpesvirus-4 strainsVeterinary Microbiology, 1988
- Studies on the Pathogenesis of a Bovine Cytomegalo-like Virus in an Experimental HostJournal of General Virology, 1985
- Analysis of Bovine Cytomegalovirus Genome Structure: Cloning and Mapping of the Monomeric Polyrepetitive DNA Unit, and Comparison of European and American StrainsJournal of General Virology, 1985
- Bovine Cytomegaloviruses: Identification and Differential PropertiesJournal of General Virology, 1984
- A new bovine herpesvirus and its effect on experimentally infected calvesArchiv für die gesamte Virusforschung, 1971