Hypothermia of newborns is associated with excess mortality in the first 2 months of life in Guinea‐Bissau, West Africa
- 28 July 2008
- journal article
- Published by Wiley in Tropical Medicine & International Health
- Vol. 13 (8), 980-986
- https://doi.org/10.1111/j.1365-3156.2008.02113.x
Abstract
To examine the long-term effects of neonatal hypothermia (HT) on survival. Using the longitudinal community and hospital surveillance system of the Bandim Health Project, we followed children born between 1997 and 2002 at the only maternity ward in the city. All children's axillary temperature was measured within 12 h of birth. They were followed from birth to 6 months of life through regular home visits. We identified 2926 live births in the study area and 177 deaths before 6 months of age. Based on mortality risk, we defined a temperature below 34.5 degrees C as the cut-off point for HT. Two hundred and thirty-eight (8%) children had HT. Controlled for birth weight, HT was associated with a nearly fivefold increase in mortality during the first 7 days of life [mortality ratio (MR) = 4.81 (2.90-8.00)] and with increased mortality from 8 to 56 days of life [MR = 2.55 (1.29-5.04)]. HT is associated with excess mortality beyond the perinatal period up to at least 2 months of age, especially among low-birth-weight children. Hence, failure to comply with the WHO guidelines for care of newborns in low-income countries may have long-term consequences for child survival which have not previously been assessed. The WHO definition of HT should be based on mortality data.This publication has 20 references indexed in Scilit:
- Neonatal Hypothermia in Uganda: Prevalence and Risk FactorsJournal of Tropical Pediatrics, 2005
- Evidence-based, cost-effective interventions: how many newborn babies can we save?The Lancet, 2005
- Why Do Neonates Die in Rural Gadchiroli, India? (Part I): Primary Causes of Death Assigned by Neonatologist Based on Prospectively Observed RecordsJournal of Perinatology, 2005
- The Incidence of Morbidities in a Cohort of Neonates in Rural Gadchiroli, India: Seasonal and Temporal Variation and a Hypothesis About PreventionJournal of Perinatology, 2005
- Hypothermia on Admission: a Risk Factor for Death in Newborns Referred to the Pernambuco Institute of Mother and Child HealthJournal of Tropical Pediatrics, 2003
- Impact of environmental temperature on response of neonatal pigs to an endotoxin challengeAmerican Journal of Veterinary Research, 2001
- The EPICure Study: Outcomes to Discharge From Hospital for Infants Born at the Threshold of ViabilityPEDIATRICS, 2000
- Hypoglycaemia: a Common Problem Among Uncomplicated Newborn Infants in NepalJournal of Tropical Pediatrics, 1993
- Colostrum and ideas about bad milk: A case study from Guinea-BissauSocial Science & Medicine (1982), 1993
- Lower body temperatures in infants delivered by caesarean section than in vaginally delivered infantsActa Paediatrica, 1993