Risk of Cardiovascular Disease and Mortality in Young Adults With End-stage Renal Disease

Abstract

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in children and adults with end-stage renal disease (ESRD).1 In adults 45 years or older, 87% have CVD reported at the time of ESRD onset, and approximately 50% of deaths are attributed to CVD.2 In children with ESRD, mortality is attributed to CVD in 23% of children in the United States and up to 50% in other countries.3,4 While early investigations provide insight into the CVD-associated health status of children and adults with ESRD, they do not adequately describe the burden of CVD in young adults (ages 22-29 years) with ESRD.