Quantitative Analysis of Methyl Parathion Pesticides in a Polydimethylsiloxane Microfluidic Channel Using Confocal Surface-Enhanced Raman Spectroscopy
- 1 April 2006
- journal article
- research article
- Published by SAGE Publications in Applied Spectroscopy
- Vol. 60 (4), 373-377
- https://doi.org/10.1366/000370206776593762
Abstract
A fast and ultra-sensitive trace analysis of methyl parathion pesticides in a polydimethylsiloxane (PDMS) microfluidic channel was investigated using confocal surface-enhanced Raman spectroscopy (SERS). A three-dimensional PDMS-based passive micromixer was fabricated for this purpose. This PDMS micromixer showed a high mixing efficiency because a strong chaotic advection was developed by the simultaneous vertical and transverse dispersion of the confluent streams. The confocal SERS signal was measured after methyl parathion pesticides were effectively adsorbed onto silver nanoparticles while flowing along the upper and lower alligator-teeth-shaped PDMS channel. A quantitative analysis of the methyl parathion pesticides was performed based on the measured peak height at 1246 cm−1. Our method has a detection limit of 0.1 ppm. This value satisfies the requirement recommended by the Collaborative International Pesticides Analytical Council (CIPAC) for the determination of methyl parathion in pesticide formulations. This study demonstrates the feasibility of using confocal SERS for the highly sensitive detection of methyl parathion pesticides in a PDMS microfluidic channel.Keywords
This publication has 23 references indexed in Scilit:
- Quantitative NIR–Raman analysis of methyl-parathion pesticide microdroplets on aluminum substratesSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2004
- Solid-phase micro-extraction–gas chromatography–(tandem) mass spectrometry as a tool for pesticide residue analysis in water samples at high sensitivity and selectivity with confirmation capabilitiesJournal of Chromatography A, 2004
- Univariate and Multivariate Calibration for the Quantitative Determination of Methyl-Parathion in Pesticide Formulations by FT-Raman SpectroscopyApplied Spectroscopy, 2000
- Analysis of Pesticides in Water Samples Using GC-ECD and GC-MS/MS TechniquesInternational Journal of Environmental Analytical Chemistry, 1999
- The response of screen-printed enzyme electrodes containing cholinesterases to organo-phosphates in solution and from commercial formulationsBiosensors and Bioelectronics, 1997
- Rapid method for the analysis of a variety of chemical classes of pesticides in surface and ground waters by off-line solid-phase extraction and gas chromatography-ion trap mass spectrometryJournal of Chromatography A, 1996
- Development of a semi-automated high-performance liquid chromatographic-diode array detection system for screening pesticides at trace levels in aquatic systems of the Axios River basinJournal of Chromatography A, 1996
- PesticidesJournal of Nutritional & Environmental Medicine, 1996
- Photometric determination of malathion with molybdenumTalanta, 1990
- Surface-enhanced Raman spectrometry of organo phosphorus chemical agentsAnalytical Chemistry, 1987