A prospective study of Type 2 diabetes and depressive symptoms in the elderly: The Rancho Bernardo Study
- 20 October 2004
- journal article
- Published by Wiley in Diabetic Medicine
- Vol. 21 (11), 1185-1191
- https://doi.org/10.1111/j.1464-5491.2004.01315.x
Abstract
Aims The association between Type 2 diabetes and depressive symptoms was examined prospectively to assess possible causal relationships between the two diseases. Methods A cohort of 971 men and women aged 50 and older from the adult population of Rancho Bernardo, California had an oral glucose tolerance test and completed the Beck Depression Inventory (BDI) at two clinic visits, 1984–87 and 1992–96. Results Depressive symptoms at baseline were associated with higher follow‐up levels of non‐fasting plasma glucose (P = 0.001) and an increased risk of developing Type 2 diabetes [odds ratio (OR) = 2.50; 95% confidence interval (CI) = 1.29–4.87], independent of sex, age, exercise and body mass index. Conversely, baseline non‐fasting plasma glucose was not significantly associated with follow‐up depressive symptoms and Type 2 diabetes at baseline was not significantly associated with the onset of BDI scores ≥ 11 by the second visit (OR = 0.73; 95% CI = 0.41–1.30). Conclusions Depressed mood is more likely to be a risk factor for Type 2 diabetes in older adults than the reverse.Keywords
This publication has 36 references indexed in Scilit:
- Relations of diabetes intrusiveness and personal control to symptoms of depression among adults with diabetes.Health Psychology, 1999
- Manipulating self-efficacy in the exercise environment in women: Influences on affective responses.Health Psychology, 1999
- Depression and Risk for Onset of Type II Diabetes: A prospective population-based studyDiabetes Care, 1996
- Brain Serotonin, Carbohydrate‐Craving, Obesity and DepressionObesity Research, 1995
- Prevalence of Cardiovascular and Renal Complications in Older Adults With Normal or Impaired Glucose Tolerance or NIDDM: A population-based studyDiabetes Care, 1993
- Depression and immunity: A meta-analytic review.Psychological Bulletin, 1993
- Chronic illness and depressive symptoms in the elderly: A population-based studyJournal of Clinical Epidemiology, 1990
- Depressive Symptomatology in Obese Adults With Type II DiabetesDiabetes Care, 1990
- Reliability and validity of screening scales: Effect of reducing scale lengthJournal of Clinical Epidemiology, 1989
- Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluationClinical Psychology Review, 1988