Extensive Homologous Recombination among Widely Divergent TT Viruses
- 15 August 2000
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 74 (16), 7666-7670
- https://doi.org/10.1128/jvi.74.16.7666-7670.2000
Abstract
Analyses of a collection of full-length TT virus genomes showed nearly half of them to be recombinant. The results were highly significant and revealed homologous recombination both within and among genotypes, often involving extremely divergent lineages. Recombination breakpoints were significantly more common in the noncoding region of the TT virus genome than in the coding region.Keywords
This publication has 23 references indexed in Scilit:
- Evolutionary aspects of recombination in RNA virusesJournal of General Virology, 1999
- The Entire Nucleotide Sequence of a TT Virus Isolate from the United States (TUS01): Comparison with Reported Isolates and Phylogenetic AnalysisVirology, 1999
- Complete Circular DNA Genome of a TT Virus Variant (Isolate Name SANBAN) and 44 Partial ORF2 Sequences Implicating a Great Degree of Diversity beyond GenotypesVirology, 1999
- Marked Genomic Heterogeneity and Frequent Mixed Infection of TT Virus Demonstrated by PCR with Primers from Coding and Noncoding RegionsVirology, 1999
- Multiple Infection ofTT Virus(TTV) with Different Genotypes in Japanese HemophiliacsBiochemical and Biophysical Research Communications, 1999
- Very high prevalence of TT virus (TTV) infection in general population of Japan revealed by a new set of PCR primersHepatology Research, 1998
- Molecular cloning and characterization of a novel DNA virus (TTV) associated with posttransfusion hepatitis of unknown etiologyHepatology Research, 1998
- A Novel DNA Virus (TTV) Associated with Elevated Transaminase Levels in Posttransfusion Hepatitis of Unknown EtiologyBiochemical and Biophysical Research Communications, 1997
- Cross-species transmission and recombination of ‘AIDS’ virusesPhilosophical Transactions Of The Royal Society B-Biological Sciences, 1995
- CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceNucleic Acids Research, 1994