Influenza Escapes Immunity Along Neutral Networks
- 22 December 2006
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 314 (5807), 1884-1886
- https://doi.org/10.1126/science.1137300
Abstract
Given that influenza virus continues to escape immunity, why is it that only one strain dominates each year? The answer may lie in neutral networks and mapping viral genotypes to antigenic phenotypes.This publication has 19 references indexed in Scilit:
- Epochal Evolution Shapes the Phylodynamics of Interpandemic Influenza A (H3N2) in HumansScience, 2006
- Mapping the Antigenic and Genetic Evolution of Influenza VirusScience, 2004
- Predicting the Evolution of Human Influenza AScience, 1999
- Continuity in Evolution: On the Nature of TransitionsScience, 1998
- Finite populations induce metastability in evolutionary searchPhysics Letters A, 1997
- Punctuated Evolution Caused by Selection of Rare Beneficial MutationsScience, 1996
- Smoothness within ruggedness: the role of neutrality in adaptation.Proceedings of the National Academy of Sciences of the United States of America, 1996
- From sequences to shapes and back: a case study in RNA secondary structuresProceedings. Biological sciences, 1994
- Theory for protein mutability and biogenesis.Proceedings of the National Academy of Sciences of the United States of America, 1990
- Evolutionary Rate at the Molecular LevelNature, 1968