Menopausal cardiomyopathy: Does it really exist? A case-control deformation imaging study
- 2 June 2014
- journal article
- Published by Wiley in Journal of Obstetrics and Gynaecology Research
- Vol. 40 (6), 1748-1753
- https://doi.org/10.1111/jog.12368
Abstract
We aimed to evaluate and compare the left ventricular (LV) functions of pre- and postmenopausal women at similar ages with none of the known cardiovascular risk factors, by both conventional and advanced echocardiographic methods such as 2-D strain imaging via speckle tracking echocardiography. The study population consisted of 40 healthy postmenopausal women aged 45-50 years and 40 healthy premenopausal women of the same age group. None of the subjects had any cardiovascular risk factors and were on hormone replacement therapy. LV strain and strain rate parameters were measured by 2-D strain imaging. The main outcome measure was effect of menopause on LV function. There were no significant differences between the pre- and postmenopausal groups with regard to conventional echocardiographic parameters. LV longitudinal strain and LV early diastolic strain rate values were significantly lower in the postmenopausal group when compared to the premenopausal group. Also, there was a significant negative correlation between LV global strain and serum follicle-stimulating hormone (r = -0.349, P = 0.002). Our study results demonstrated that healthy postmenopausal women had lower LV longitudinal strain values when compared to the healthy premenopausal women of the same age group by speckle tracking echocardiography.Keywords
This publication has 25 references indexed in Scilit:
- Assessment of Right Ventricular Mechanics in Patients with Mitral Stenosis by Two-Dimensional Deformation ImagingEchocardiography, 2012
- Executive Summary of the Stages of Reproductive Aging Workshop+10: Addressing the Unfinished Agenda of Staging Reproductive AgingJournal of Clinical Endocrinology & Metabolism, 2012
- Decreased Mechanical Function of Left Atrium Assessed by Speckle Tracking and Tissue Doppler Echocardiography in Patients with Congestive Heart FailureJournal of Medical Ultrasound, 2012
- Relationship between Oxidative Stress and Cardiomyopathic Changes in Ovariectomized RatsJMIR AI, 2011
- Severity of Mitral Stenosis and Left Ventricular Mechanics: A Speckle Tracking StudyJMIR AI, 2011
- Current and Evolving Echocardiographic Techniques for the Quantitative Evaluation of Cardiac Mechanics: ASE/EAE Consensus Statement on Methodology and Indications Endorsed by the Japanese Society of EchocardiographyEuropean Heart Journal - Cardiovascular Imaging, 2011
- Managing cardiovascular risk in menopausal womenClimacteric, 2006
- Effect of menopause on left ventricular filling in 50-year-old womenThe American Journal of Cardiology, 1995
- Recommendations for Quantitation of the Left Ventricle by Two-Dimensional EchocardiographyJournal of the American Society of Echocardiography, 1989
- Menopause and Risk of Cardiovascular DiseaseAnnals of Internal Medicine, 1976