Topological Indices Study of Molecular Structure in Anticancer Drugs
Open Access
- 1 January 2016
- journal article
- Published by Hindawi Limited in Journal of Chemistry
- Vol. 2016, 1-8
- https://doi.org/10.1155/2016/3216327
Abstract
Topological Indices Study of Molecular Structure in Anticancer Drugs: Numerous studies indicate that there is strong inherent relationship between the chemical characteristics of chemical compounds and drugs (e.g., boiling point and melting point) and their molecular structures. Topological indices defined on these chemical molecular structures can help researchers better understand the physical features, chemical reactivity, and biological activity. Thus, the study of the topological indices on chemical structure of chemical materials and drugs can make up for lack of chemical experiments and can provide a theoretical basis for the manufacturing of drugs and chemical materials. In this paper, we focus on the family of smart polymer which is widely used in anticancer drugs manufacturing. Several topological indices are determined in view of edge dividing methods, and these results remedy the lack of chemical and medicine experiments thus providing the theoretical basis for pharmaceutical engineering.Keywords
Funding Information
- National Natural Science Foundation of China (11401519, 11371328, 11471293)
This publication has 23 references indexed in Scilit:
- The Vertex Version of Weighted Wiener Number for Bicyclic Molecular StructuresComputational and Mathematical Methods in Medicine, 2015
- General Harmonic Index and General Sum Connectivity Index of Polyomino Chains and NanotubesJournal of Computational and Theoretical Nanoscience, 2015
- Second Atom-Bond Connectivity Index of Special Chemical Molecular StructuresJournal of Chemistry, 2014
- Wiener Index of Gear Fan Graph and Gear Wheel GraphAsian Journal of Chemistry, 2014
- The smallest Randić index for treesProceedings - Mathematical Sciences, 2013
- The harmonic index for graphsApplied Mathematics Letters, 2012
- On general sum-connectivity indexJournal of Mathematical Chemistry, 2009
- Perspective on the Relationship between Melting Points and Chemical StructureCrystal Growth & Design, 2001
- Some eigenvalue properties in graphs (conjectures of Graffiti — II)Discrete Mathematics, 1993
- Structural Determination of Paraffin Boiling PointsJournal of the American Chemical Society, 1947