HyperendemicStreptococcus pyogenesInfection despite Prophylaxis with Penicillin G Benzathine

Abstract
In closely confined populations, in which epidemics of Streptococcus pyogenes infection are common, penicillin G benzathine has long been used prophylactically to reduce morbidity from this pathogen. We report on our investigations of the effectiveness of penicillin G benzathine prophylaxis at a military recruit camp.