Sleeping and Breathing

Abstract

He sleeps well who knows not that he sleeps ill. (Latin proverb)Clinical investigation has provided many examples of disturbances in normal physiology and biochemistry in which the function of a carefully integrated system is disrupted because of circumscribed defects in one component or link in the system. It is remarkable in this regard that discrete defects in the complex process of the regulation of pulmonary ventilation were late in coming to the attention of physiologists and clinicians. The concept of respiratory failure in the presence of normal lungs emerged conceptually in the middle 1950's as a result of case . . .