LOCAL TUMOUR CELL SEEDING BY FINE‐NEEDLE ASPIRATION BIOPSY
- 1 July 1983
- journal article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Series A :Pathology
- Vol. 91A (1-6), 17-21
- https://doi.org/10.1111/j.1699-0463.1983.tb02721.x
Abstract
We have performed fine-needle biopsies from solid or ascites-growing mouse tumours. The biopsies were taken via striated muscle or the peritoneal cavity of healthy mice syngeneic with the tumours and the tumour-bearing animals. The incidence of tumour takes in these new mice were compared with the intramuscular or intraperitoneal transplantability of the tumours. In order to estimate more accurately the number of seeded cells, we also performed aspiration biopsy through the leg muscles of healthy animals into ascites-growing tumours labelled with 125IUDR. The resulting radioactivity in the leg muscle was compared with the radioactivity of the ascites tumour cells. The studies indicate that one may seed 10(3)-10(4) cells, and sometimes more, into the needle track with fine-needle aspiration biopsy from extremely cellular and dedifferentiated tumors.Keywords
This publication has 15 references indexed in Scilit:
- 125IUDR labelling efficiency and cytotoxicity for murine tumours in vivo and in vitroEuropean Journal of Nuclear Medicine and Molecular Imaging, 1982
- Alteration of a tumor cell distribution pattern by cytochalasin BPathology - Research and Practice, 1981
- Malignant Seeding of the Tract after Thin-Needle Aspiration BiopsyRadiology, 1979
- Ascites tumors in CBA miceZeitschrift für Krebsforschung und Klinische Onkologie, 1979
- Needle tract seeding of renal cell carcinomaAmerican Journal of Roentgenology, 1977
- Implantation Metastasis after Percutaneous Transthoracic Needle Aspiration BiopsyActa Radiologica. Diagnosis, 1976
- Investigation on Tumour Spread in Connection with Aspiration BiopsyActa Radiologica: Therapy, Physics, Biology, 1971
- Incorporation of 125Iodine-Labeled 5-Iodo-2′-Deoxyuridine into the DNA of Mouse Mammary TumorsPublished by Springer Science and Business Media LLC ,1969
- Investigations of Host Resistance in Cancer PatientsAnnals of Surgery, 1958