Spatial and temporal analysis of tuberculosis in Zhejiang Province, China, 2009-2012
Open Access
- 23 February 2016
- journal article
- research article
- Published by Springer Science and Business Media LLC in Infectious Diseases of Poverty
- Vol. 5 (1), 1-10
- https://doi.org/10.1186/s40249-016-0104-2
Abstract
Tuberculosis (TB) is an infectious disease of major public health concern. The disease has demonstrated large space-time variations. This study aims to explore the space-time dynamics of TB cases in an economically and geographically dynamic province in China with specific references of TB control for policy makers. Data on all reported TB cases from 2009 to 2012 were collected from the TB program at the Zhejiang Provincial Center for Disease Control and Prevention. We employed time series and exploratory spatial data analyses, including Moran’s I, Local Getis’s G i * , and Kulldorff’s space-time scan statistics, to identify the temporal trends and spatial patterns of TB at a county level. A total of 147,941 TB cases were reported during 2009–2012 in Zhejiang. A higher proportion of TB cases were younger, male, and registered permanent residents among all TB cases notified in the province. TB cases were reported most frequently in April with small peaks in June, July, and October. This disease was spatially clustering with Moran’s I values ranged from 0.29 to 0.32 (p < 0.001). A most likely cluster and ten secondary clusters were identified, mainly concentrated in the southeast and west counties of the province. This study identified seasonal patterns and significant space-time clusters of TB cases in Zhejiang, China. Poverty, migration, and seasonal effects may play important roles in potential clusters.Funding Information
- Hong Kong Research Grant Council (14411614)
This publication has 42 references indexed in Scilit:
- Detecting Spatial-Temporal Clusters of HFMD from 2007 to 2011 in Shandong Province, ChinaPLOS ONE, 2013
- Comparing patient care seeking pathways in three models of hospital and TB programme collaboration in ChinaBMC Infectious Diseases, 2013
- The spatial epidemiology of tuberculosis in Linyi City, China, 2005–2010BMC Public Health, 2012
- A national study of socioeconomic status and tuberculosis rates by country of birth, United States, 1996–2005BMC Public Health, 2012
- Assessing trends and predictors of tuberculosis in TaiwanBMC Public Health, 2012
- Spatial epidemiology and spatial ecology study of worldwide drug-resistant tuberculosisInternational Journal of Health Geographics, 2011
- Using the SaTScan method to detect local malaria clusters for guiding malaria control programmesMalaria Journal, 2009
- Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern CambodiaMalaria Journal, 2009
- Mapping H5N1 highly pathogenic avian influenza risk in Southeast AsiaProceedings of the National Academy of Sciences of the United States of America, 2008
- Geographic prediction of tuberculosis clusters in Fukuoka, Japan, using the space-time scan statisticBMC Infectious Diseases, 2007