Phosphorus flame retardants in indoor dust and their relation to asthma and allergies of inhabitants
- 1 June 2013
- journal article
- research article
- Published by Hindawi Limited in Indoor Air
- Vol. 24 (1), 3-15
- https://doi.org/10.1111/ina.12054
Abstract
Organophosphate esters are used as additives in flame retardants and plasticizers, and they are ubiquitous in the indoor environment. Phosphorus flame retardants (PFRs) are present in residential dust, but few epidemiological studies have assessed their impact on human health. We measured the levels of 11 PFRs in indoor floor dust and multi‐surface dust in 182 single‐family dwellings in Japan. We evaluated their correlations with asthma and allergies of the inhabitants. Tris(2‐butoxyethyl) phosphate was detected in all samples (median value: 580 μg/g in floor dust, 111 μg/g in multi‐surface dust). Tris(2‐chloro‐iso‐propyl) phosphate (TCIPP) was detected at 8.69 μg/g in floor dust and 25.8 μg/g in multi‐surface dust. After adjustment for potential confounders, significant associations were found between the prevalence of atopic dermatitis and the presence of TCIPP and tris(1,3‐dichloro‐2‐propyl) phosphate in floor dust [per log10‐unit, odds ratio (OR): 2.43 and 1.84, respectively]. Tributyl phosphate was significantly associated with the prevalence of asthma (OR: 2.85 in floor dust, 5.34 in multi‐surface dust) and allergic rhinitis (OR: 2.55 in multi‐surface dust). PFR levels in Japan were high compared with values reported previously for Europe, Asia‐Pacific, and the USA. Higher levels of PFRs in house dust were related to the inhabitants' health status.Keywords
This publication has 44 references indexed in Scilit:
- A novel abbreviation standard for organobromine, organochlorine and organophosphorus flame retardants and some characteristics of the chemicalsEnvironment International, 2012
- Occurrence of alternative flame retardants in indoor dust from New Zealand: Indoor sources and human exposure assessmentChemosphere, 2012
- The relationship between exposure to microbial volatile organic compound and allergy prevalence in single-family homesScience of The Total Environment, 2012
- Comparisons of polybrominated diphenyl ether and hexabromocyclododecane concentrations in dust collected with two sampling methods and matched breast milk samplesIndoor Air, 2012
- Assessment of human exposure to indoor organic contaminants via dust ingestion in PakistanIndoor Air, 2011
- Organophosphate and phthalate esters in air and settled dust - a multi-location indoor studyIndoor Air, 2010
- Relationship between selected indoor volatile organic compounds, so-called microbial VOC, and the prevalence of mucous membrane symptoms in single family homesScience of The Total Environment, 2010
- Diffusive sampling and measurement of microbial volatile organic compounds in indoor airIndoor Air, 2009
- Primary prevention of asthma and allergyJournal of Allergy and Clinical Immunology, 2005
- Emission of phthalates from PVC and other materialsIndoor Air, 2004