Anesthetic Efficacy of Different Ropivacaine Concentrations for Inferior Alveolar Nerve Block
Open Access
- 1 March 2006
- journal article
- research article
- Published by American Dental Society of Anesthesiology (ADSA) in Anesthesia Progress
- Vol. 53 (1), 3-7
- https://doi.org/10.2344/0003-3006(2006)53[3:aeodrc]2.0.co;2
Abstract
This study was conducted on 72 American Society of Anesthesiologists class 1 patients scheduled for extraction of a mandibular third molar after inferior alveolar nerve block. Each patient was randomly administered one of the following ropivacaine concentrations: 0.75%, 0.5%, 0.375%, or 0.25% (18 patients per group). Onset of block (mean +/- SD) was rapid for both 0.75% (1.4 +/- 0.4 minutes) and 0.5% (1.7 +/- 0.5 minutes) ropivacaine but significantly slower for the 0.375% (4.2 +/- 2.5 minutes) and 0.25% (10.7 +/- 3.0 minutes) concentrations. Tooth extraction was performed successfully with the 0.5% and 0.75% concentrations, and supplemental injections were not required. Second injections, however, were required with 0.375% ropivacaine. Anesthesia was unsuccessful in 13 patients given 0.25% ropivacaine even after 3 injections. The mean durations of soft tissue anesthesia were 3.3 +/- 0.3 hours and 3.0 +/- 0.3 hours for the 0.75% and 0.5% concentrations, but significantly shorter with more dilute concentrations. The duration of analgesia showed a similar pattern, with the 0.75% and 0.5% concentrations producing prolonged analgesia of 6.0 +/- 0.4 hours and 5.6 +/- 0.4 hours. These results indicate that 0.5% and 0.75% concentrations were effective for intraoral nerve blockade, with both a rapid onset and prolonged duration of pain control.Keywords
This publication has 15 references indexed in Scilit:
- The efficacy of ropivacaine as a dental local anaesthetic.2004
- Ropivacaine for dental anesthesia: A dose-finding studyJournal of Oral and Maxillofacial Surgery, 2002
- A comparison of ropivacaine and lidocaine with epinephrine for intraligamentary anesthesiaOral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 2002
- Anesthetic efficacy of ropivacaine in maxillary anterior infiltrationOral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 2001
- Evaluation of efficacy and plasma concentrations of ropivacaine in continuous axillary brachial plexus block: High dose for surgical anesthesia and low dose for postoperative analgesiaRegional Anesthesia & Pain Medicine, 2000
- Interscalene brachial plexus anaesthesia with 0.5%, 0.75% or 1% ropivacaine: a double-blind comparison with 2% mepivacaineBritish Journal of Anaesthesia, 1999
- AN OPEN STUDY OF ROPIVACAINE IN EXTRADURAL ANAESTHESIABritish Journal of Anaesthesia, 1990
- STRUCTURE—ACTIVITY RELATIONSHIPS IN DIFFERENTIAL NERVE BLOCK AT HIGH AND LOW FREQUENCY STIMULATIONBritish Journal of Anaesthesia, 1989
- Primary evaluation of the local anaesthetic properties of the amino amide agent ropivacaine (LEA 103)Acta Anaesthesiologica Scandinavica, 1988
- DIFFERENTIAL SENSITIVITY OF A AND C NERVE FIBRES TO LONG-ACTING AMIDE LOCAL ANAESTHETICSBritish Journal of Anaesthesia, 1983