Results and Complications of Laser in situ Keratomileusis by Experienced Surgeons

Abstract
To identify intraoperative and early postoperative adverse events and complications that may be encountered after the laser in-situ keratomileusis (LASIK) learning process. One hundred sixty-nine consecutive eyes of 108 patients who had LASIK by a surgeon experienced in LASIK were studied. All intraoperative and early postoperative adverse events and complications were noted. Patients were examined at 1 day and 1 to 3 months after surgery. Six baseline refractive groups were studied: high myopia with astigmatism (-10.25 to -17.50 D; 18 eyes), moderate myopia with astigmatism (-6.00 to -9.50 D; 31 eyes), low myopia with astigmatism (-0.75 to -5.87 D; 81 eyes), mixed astigmatism (-0.25 to +0.50 D; 6 eyes), low to moderate hyperopia with astigmatism (+1.00 to +3.75 D; 19 eyes), and high hyperopia with astigmatism (+4.25 to +7.37 D; 12 eyes). Seventy-eight percent (132 eyes) had a primary LASIK procedure; 22% (37 eyes) had LASIK after previous refractive surgery. Primary and secondary LASIK procedures were analyzed together. The Nidek EC-5000 or the Chiron PlanoScan excimer lasers were used. The most commonly observed adverse intraoperative events were minor corneal bleeding (3%) and thin flap (1%). The most commonly observed postoperative events were punctate epithelial keratopathy (6%) and small epithelial defect 1 day after surgery (5%). The most serious complication occurred in three eyes with preoperative high hyperopia (spherical equivalent refraction greater than +4.00 D) in which corneal topographic abnormalities resulted. At last examination, mean postoperative spherical equivalent refraction was less than +1.00 D in all groups. Spectacle-corrected visual acuity was 20/20 in 70 eyes (41%) and 20/25 or better in 119 eyes (70%). Loss of spectacle-corrected visual acuity of two or more lines occurred in five eyes (3%), three of which had preoperative high hyperopia with abnormal postoperative corneal topography. Our prospective study should help LASIK surgeons gauge their expectations of intraoperative and early postoperative complications. Surgeons should proceed cautiously when treating patients with high hyperopia, because a higher incidence of loss of spectacle-corrected visual acuity may be encountered postoperatively.