SCLEROSING LIPOGRANULOMA OF MALE GENITALIA - REVIEW OF 23 CASES

Abstract

In 1950 the term sclerosing lipogranuloma was introduced to designate a particular subcutaneous granulomatous reaction that was believed to be a local reactive process following injury to adipose tissue. Subsequent reports showed that exogenous lipid injections probably are responsible for this lesion. Cases were studied involving penis, scrotum, spermatic cord and perineum, 9 of which were previously reported were identified. Paraffin hydrocarbons by IR-absorption spectrophotometry in 21 of these cases. This entity probably should be redefined as a local reactive process following injection of exogenous lipids into the subcutaneous tissues. In conventional microscopical sections, the lesion must be differentiated from adenomatoid tumor, sclerosing liposarcoma and lymphangioma.