On the relationship between neurocysticercosis and mesial temporal lobe epilepsy associated with hippocampal sclerosis: coincidence or a pathogenic relationship?
- 1 September 2012
- journal article
- review article
- Published by Informa UK Limited in Pathogens and Global Health
- Vol. 106 (5), 280-285
- https://doi.org/10.1179/2047773212y.0000000027
Abstract
Neurocysticercosis (NCC) and mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE-HS) are two common worldwide forms of focal epilepsy. In regions where NCC is endemic, both diseases can be observed in the same patient. There is recent and growing evidence suggesting that NCC might contribute to or even cause MTLE-HS. In this article, we review the literature regarding NCC and temporal lobe epilepsy, specifically addressing the relationship between NCC and MTLE-HS. In addition, we review some scenarios where NCC seems to emerge as a causative agent or contributor to the development of MTLE-HS in some patients. This association is important because it may have an impact on the evaluation and treatment of a sizable proportion of patients with epilepsy. Insights from these clinical observations might also contribute to the understanding of the neurobiology of both NCC and MTLE-HS. We hope that our review might shed some light on this interesting interplay between two of the most common worldwide conditions associated with human focal epilepsy.Keywords
This publication has 44 references indexed in Scilit:
- Diagnosis and treatment of neurocysticercosisNature Reviews Neurology, 2011
- Clinical Manifestations Associated with Neurocysticercosis: A Systematic ReviewPLoS Neglected Tropical Diseases, 2011
- How frequent is the association of neurocysticercosis and mesial temporal lobe epilepsy with hippocampal sclerosis?Epilepsia, 2010
- COGNITIVE IMPAIRMENT AND DEMENTIA IN NEUROCYSTICERCOSIS: A CROSS-SECTIONAL CONTROLLED STUDYNeurology, 2010
- Calcified cysticercotic lesions and intractable epilepsy: a cross sectional study of 512 patientsJournal of Neurology, Neurosurgery & Psychiatry, 2006
- Mesial Temporal Lobe Epilepsy with Hippocampal SclerosisEpilepsia, 2004
- Neurocysticercosis in West LondonArchives of Disease in Childhood, 2003
- The epidemiology of epilepsy revisitedCurrent Opinion in Neurology, 2003
- Neurocysticercosis and epilepsy in developing countriesJournal of Neurology, Neurosurgery & Psychiatry, 2000
- Influence of the type of initial precipitating injury and at what age it occurs on course and outcome in patients with temporal lobe seizuresJournal of Neurosurgery, 1995