Partitioning of polybrominated diphenyl ether (PBDE) congeners in human blood and milk
- 1 April 2006
- journal article
- research article
- Published by Taylor & Francis Ltd in Toxicological & Environmental Chemistry
- Vol. 88 (2), 319-324
- https://doi.org/10.1080/02772240600605087
Abstract
Polybrominated diphenyl ethers (PBDEs) are brominated flame retardants (BFRs) which have recently been detected in human blood and milk in the USA, and presently these PBDE levels are found to be the highest globally. On a population basis, individual blood and individual milk analyses show similar congener patterns and levels. Until now, there has not been a study comparing PBDE levels in milk and blood of the same individuals. This study is the first to report these levels for PBDEs, though partitioning between blood and milk has been done previously for dioxins and polychlorinated biphenyls (PCBs). Twelve congeners in 11 nursing mothers’ blood and milk were found and the data describe partitioning ratios between blood and milk. The data suggest it may be easier for smaller, less brominated congeners to move from blood to milk.Keywords
This publication has 7 references indexed in Scilit:
- Brominated flame retardants: cause for concern?Environmental Health Perspectives, 2004
- Polybrominated diphenyl ethers (PBDEs) in U.S. mothers' milk.Environmental Health Perspectives, 2003
- Neurobehavioral Derangements in Adult Mice Receiving Decabrominated Diphenyl Ether (PBDE 209) during a Defined Period of Neonatal Brain DevelopmentToxicological Sciences, 2003
- Placental Transfer of a Hydroxylated Polychlorinated Biphenyl and Effects on Fetal and Maternal Thyroid Hormone Homeostasis in the RatToxicological Sciences, 2002
- Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats—testing interactions and mechanisms for thyroid hormone effectsToxicology, 2002
- A Brominated Flame Retardant, 2,2`,4,4`,5-Pentabromodiphenyl Ether: Uptake, Retention, and Induction of Neurobehavioral Alterations in Mice during a Critical Phase of Neonatal Brain DevelopmentToxicological Sciences, 2002
- In vitro estrogenicity of polybrominated diphenyl ethers, hydroxylated PDBEs, and polybrominated bisphenol A compounds.Environmental Health Perspectives, 2001