Lockdown Contained the Spread of 2019 Novel Coronavirus Disease in Huangshi City, China: Early Epidemiological Findings
- 7 April 2020
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 71 (6), 1454-1460
- https://doi.org/10.1093/cid/ciaa390
Abstract
Background To control the spread of 2019 novel coronavirus disease (COVID-19), China sealed Wuhan on 23 January 2020 and soon expanded lockdown to 12 other cities in Hubei province. We aimed to describe the epidemiological characteristics in one of the cities and highlight the effect of current implemented lockdown and nonpharmaceutical interventions. Methods We retrieved data of reported cases in Huangshi and Wuhan from publicly available disease databases. Local epidemiological data on suspected or confirmed cases in Huangshi were collected through field investigation. Epidemic curves were constructed with data on reported and observed cases. Results The accumulated confirmed COVID-19 cases and fatality in Huangshi were reported to be 1015 and 3.74%, respectively, compared with 50006 and 5.08% in Wuhan until 27 March 2020. Right after 24 January, the epidemic curve based on observed cases in Huangshi became flattened. And 1 February 2020 was identified as the “turning point” as the epidemic in Huangshi faded soon afterward. COVID-19 epidemic was characterized by mild cases in Huangshi, accounting for 82.66% of total cases. Moreover, 50 asymptomatic infections were identified in adults and children. In addition, we found confirmed cases in 19 familial clusters and 21 healthcare workers, supporting interhuman transmission. Conclusions Our study reported the temporal dynamics and characteristics of the COVID-19 epidemic in Huangshi city, China, across the unprecedented intervention. Such new epidemiological inference might provide further guidance on current lockdown measures in high-risk cities and, subsequently, help improve public health intervention strategies against the pandemic on the country and global levels.Funding Information
- Jiangsu Provincial Health Committee (QNRC2016402, LGY2017039)
- Nantong municipal Bureau of Science and Technology (HS2016002)
This publication has 17 references indexed in Scilit:
- Origins of MERS-CoV, and lessons for 2019-nCoVThe Lancet Planetary Health, 2020
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, ChinaThe Lancet, 2020
- The psychological effects of quarantining a cityBMJ, 2020
- China coronavirus: mild but infectious cases may make it hard to control outbreak, report warnsBMJ, 2020
- Outbreak of pneumonia of unknown etiology in Wuhan, China: The mystery and the miracleJournal of Medical Virology, 2020
- The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, ChinaInternational Journal of Infectious Diseases, 2020
- Unraveling the drivers of MERS-CoV transmissionProceedings of the National Academy of Sciences of the United States of America, 2016
- Spatio-Temporal Synchrony of Influenza in Cities across Israel: The “Israel Is One City” HypothesisPLOS ONE, 2014
- Public health interventions and epidemic intensity during the 1918 influenza pandemicProceedings of the National Academy of Sciences of the United States of America, 2007
- Transmission Dynamics and Control of Severe Acute Respiratory SyndromeScience, 2003