Defining Adequate Surgery for Primary Melanoma
- 19 February 2004
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 350 (8), 823-825
- https://doi.org/10.1056/nejme038235
Abstract
The incidence of malignant melanoma has been rising over the past three decades.1 Much of the increase is accounted for by thin, localized cutaneous melanomas with the potential to be cured by surgery. Once melanoma spreads beyond the primary lesion, however, the likelihood of cure decreases dramatically. Five-year relative survival rates for patients with melanoma in the United States between 1992 and 1998 were 96 percent for those with local lesions but only 60 percent for patients whose melanomas had spread regionally and 14 percent for those with distant metastases.1 The thickness of the tumor and the presence or absence . . .Keywords
This publication has 9 references indexed in Scilit:
- Excision Margins in High-Risk Malignant MelanomaNew England Journal of Medicine, 2004
- Prediction of Disease Outcome in Melanoma Patients by Molecular Analysis of Paraffin-Embedded Sentinel Lymph NodesJournal of Clinical Oncology, 2003
- Detection of micrometastases in sentinel lymph nodes from melanoma patientsMelanoma Research, 2003
- Advances in Molecular Staging of Melanoma Patients: Multimarker Analysis of Archival Lymph Node TissueJournal of Clinical Oncology, 2003
- Excision Margins in the Treatment of Primary Cutaneous MelanomaArchives of Surgery, 2002
- Prognostic Factors Analysis of 17,600 Melanoma Patients: Validation of the American Joint Committee on Cancer Melanoma Staging SystemJournal of Clinical Oncology, 2001
- Vaccines for melanoma: translating basic immunology into new therapiesThe Lancet Oncology, 2001
- The Clinical Relevance of Molecular Staging for MelanomaPublished by Springer Science and Business Media LLC ,2001
- Prognostic Significance of Occult Metastases Detected by Sentinel Lymphadenectomy and Reverse Transcriptase–Polymerase Chain Reaction in Early-Stage Melanoma PatientsJournal of Clinical Oncology, 1999