The history of p53
Open Access
- 8 October 2010
- journal article
- review article
- Published by Springer Science and Business Media LLC in EMBO Reports
- Vol. 11 (11), 822-826
- https://doi.org/10.1038/embor.2010.159
Abstract
The history of p53 and the various interpretations of its function in cells serves as an example of how scientific paradigms can influence research fields. It also offers some interesting lessons for young scientists in search of a rewarding research topic.Keywords
This publication has 46 references indexed in Scilit:
- Winter Temperature and UV Are Tightly Linked to Genetic Changes in the p53 Tumor Suppressor Pathway in Eastern AsiaAmerican Journal of Human Genetics, 2009
- RNA−p53 Interactions in VitroBiochemistry, 2007
- Fog of War: The Emerging p53 FamilyCell Cycle, 2007
- Mutations in the p53 homolog p63: allele-specific developmental syndromes in humansTrends in Molecular Medicine, 2002
- The humoral response to the tumor-suppressor gene-product p53 in human cancer: implications for diagnosis and therapyImmunology Today, 1996
- Molecular mimicry reflected through database screening: serendipity or survival strategy?Immunology Today, 1996
- Chromosome 17 Deletions and p53 Gene Mutations in Colorectal CarcinomasScience, 1989
- SV40 large T-antigen and transformation related protein p53 are associated in situ with nuclear RNP structures containing hnRNA of transformed cellsExperimental Cell Research, 1986
- Use of transfection to analyze genetic information and malignant transformationBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1981
- Mutation and Cancer: Statistical Study of RetinoblastomaProceedings of the National Academy of Sciences of the United States of America, 1971