Infectivity of titered doses of simian immunodeficiency virus clone E11S inoculated intravenously into rhesus macaques (Macaca mulatta)
- 5 February 1994
- journal article
- Published by Wiley in Journal of Medical Primatology
- Vol. 23 (2-3), 83-88
- https://doi.org/10.1111/j.1600-0684.1994.tb00106.x
Abstract
The macaque infectious dose (MID) of a single-cell clone of simian immunodeficiency virus isolated from a pig-tailed macaque (SIV/Mne clone E11S) was determined in rhesus macaques (Macaca mulatta). Twenty-one macaques were inoculated with 10-fold dilutions of the virus stock (three or four animals per dose). The virologic and clinical status of these animals was monitored for 26 weeks. The 25% MID (MID25) occurred at a 105-fold dilution of the viral stock.Keywords
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