Anti‐stress and anti‐fatigue effect of fermented rice bran

Abstract

The anti‐stress and anti‐fatigue effects of a hot water extract of fermented rice bran (FRB) were investigated with Saccharomyces cerevisae IFO 2346 on rats or mice. Oral administration (1 g/kg/day) of a hot water extract of FRB inhibited major changes in weight of the adrenal, thymus, spleen and thyroid, showing the anti‐stress effect. A hot water extract of FRB also inhibited the increase of GPT and LDH activity, cholesterol and serum glucose levels. Administration (1 g/kg/day) for 2 weeks significantly prolonged the swimming time, resulting in an increase of the anti‐fatigue effect. From these results, it can be considered that FRB has an anti‐stress and anti‐fatigue effect. Copyright © 2002 John Wiley & Sons, Ltd.