Biocatalysts for selective introduction of oxygen
- 1 January 2009
- journal article
- review article
- Published by Informa UK Limited in Biocatalysis and Biotransformation
- Vol. 27 (1), 1-26
- https://doi.org/10.1080/10242420802393519
Abstract
Three types of oxygenase biocatalysts are treated in detail in this review: the non-haem iron alkene mono-oxygenases, the haem and vanadium haloperoxidases, and flavin-based Baeyer–Villiger mono-oxygenases. Other oxygenases are briefly included for comparison. Characteristics of the biocatalysts are presented, and the scope and limitations concerning their applicability for the selective introduction of oxygen are discussed. Key issues include catalytic activity, productivity, cloning and expression, as well as process engineering aspects. Various bottlenecks are identified for the different biocatalysts and measures to increase the number of oxygenase reactions in practical use are discussed.Keywords
This publication has 191 references indexed in Scilit:
- Enzyme Immobilization: The Quest for Optimum PerformanceAdvanced Synthesis & Catalysis, 2007
- Intermediates in Dioxygen Activation by Methane Monooxygenase: A QM/MM StudyJournal of the American Chemical Society, 2007
- Electroenzymatic Synthesis of Chiral SulfoxidesEngineering in Life Sciences, 2006
- Utilisation of C2–C4 gaseous hydrocarbons and isoprene by microorganismsJournal of Chemical Technology & Biotechnology, 2005
- Chloroperoxidase from Caldariomyces fumago is active in the presence of an ionic liquid as co-solventBiotechnology Letters, 2004
- Highly Enantioselective Oxidation of cis-Cyclopropylmethanols to Corresponding Aldehydes Catalyzed by ChloroperoxidaseThe Journal of Organic Chemistry, 2001
- The alkene monooxygenase from Xanthobacter Py2 is a binuclear non‐haem iron protein closely related to toluene 4‐monooxygenaseFEBS Letters, 1998
- The mechanism of methane and dioxygen activation in the catalytic cycle of methane monooxygenaseFEBS Letters, 1995
- Activation of the hydroxylase of sMMO from Methylococcus capsulatus (Bath) by hydrogen peroxideBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1993
- Peroxide oxidation of primary alcohols to aldehydes by chloroperoxidase catalysisBiochemical and Biophysical Research Communications, 1983