Systemic Lupus Erythematosus-Like Syndrome in Monkeys Fed Alfalfa Sprouts: Role of a Nonprotein Amino Acid
- 23 April 1982
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 216 (4544), 415-417
- https://doi.org/10.1126/science.7071589
Abstract
Hematologic and serologic abnormalities similar to those observed in human systemic lupus erythematosus (SLE) developed in cynomolgus macaques fed alfalfa sprouts. L-Canavanine sulfate, a constituent of alfalfa sprouts, was incorporated into the diet and reactivated the syndrome in monkeys in which an SLE-like syndrome had previously been induced by the ingestion of alfalfa seeds or sprouts.Keywords
This publication has 16 references indexed in Scilit:
- Diet-Induced Systemic Lupus Erythematosus (SLE) in PrimatesAmerican Journal of Kidney Diseases, 1982
- Alfalfa saponins and alfalfa seeds: Dietary effects in cholesterol-fed rabbitsAtherosclerosis, 1980
- Diversity of antinuclear antibodies in progressive systemic sclerosisArthritis & Rheumatism, 1980
- Studies on the metabolism of guanidine compounds in mammalsArchives of Biochemistry and Biophysics, 1979
- The Biological Effects and Mode of Action of L-Canavanine, a Structural Analogue of L-ArginineThe Quarterly Review of Biology, 1977
- The use of amino acid analogues in studies on plant metabolismPhytochemistry, 1976
- Toxic Amino Acids: Their Action as AntimetabolitesAdvances in enzymology and related subjects of biochemistry, 1967
- Control of histone and DNA synthesis with canavanine, puromycin, and poliovirusBiochemical and Biophysical Research Communications, 1965
- A New Diagnostic Test for Antiglobulin Positive (‘Auto‐Immune’) Haemolytic Anaemia*British Journal of Haematology, 1960
- Canavanine in the LeguminosaeBiochemical Journal, 1960