Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells
- 26 December 2011
- journal article
- Published by Elsevier BV in Cancer Letters
- Vol. 313 (1), 54-63
- https://doi.org/10.1016/j.canlet.2011.08.023
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- Reversal and Prevention of Arsenic-Induced Human Bronchial Epithelial Cell Malignant Transformation by microRNA-200bToxicological Sciences, 2011
- Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast CancerMolecular Cell, 2010
- Rho GTPases in cancer cell biologyFEBS Letters, 2008
- Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerationsDrug Resistance Updates, 2008
- Heregulin β1 promotes breast cancer cell proliferation through Rac/ERK-dependent induction of cyclin D1 and p21Cip1Biochemical Journal, 2008
- Trastuzumab: triumphs and tribulationsOncogene, 2007
- The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesisOncogene, 2007
- GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factorsNature Reviews Molecular Cell Biology, 2005
- Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1bOncogene, 2000
- Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu OncogeneScience, 1987