Impact of Reduced Tobacco Smoking on Lung Cancer Mortality in the United States During 1975–2000
Open Access
- 14 March 2012
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 104 (7), 541-548
- https://doi.org/10.1093/jnci/djs136
Abstract
Considerable effort has been expended on tobacco control strategies in the United States since the mid-1950s. However, we have little quantitative information on how changes in smoking behaviors have impacted lung cancer mortality. We quantified the cumulative impact of changes in smoking behaviors that started in the mid-1950s on lung cancer mortality in the United States over the period 1975–2000. A consortium of six groups of investigators used common inputs consisting of simulated cohort-wise smoking histories for the birth cohorts of 1890 through 1970 and independent models to estimate the number of US lung cancer deaths averted during 1975–2000 as a result of changes in smoking behavior that began in the mid-1950s. We also estimated the number of deaths that could have been averted had tobacco control been completely effective in eliminating smoking after the Surgeon General’s first report on Smoking and Health in 1964. Approximately 795 851 US lung cancer deaths were averted during the period 1975–2000: 552 574 among men and 243 277 among women. In the year 2000 alone, approximately 70 218 lung cancer deaths were averted: 44 135 among men and 26 083 among women. However, these numbers are estimated to represent approximately 32% of lung cancer deaths that could have potentially been averted during the period 1975–2000, 38% of the lung cancer deaths that could have been averted in 1991–2000, and 44% of lung cancer deaths that could have been averted in 2000. Our results reflect the cumulative impact of changes in smoking behavior since the 1950s. Despite a large impact of changing smoking behaviors on lung cancer deaths, lung cancer remains a major public health problem. Continued efforts at tobacco control are critical to further reduce the burden of this disease.Keywords
This publication has 24 references indexed in Scilit:
- Colorectal Cancer Incidence Trends in the United States and United Kingdom: Evidence of Right- to Left-Sided Biological Gradients with Implications for ScreeningCancer Research, 2010
- Estimation of the effects of smoking and DNA repair capacity on coefficients of a carcinogenesis model for lung cancerInternational Journal of Cancer, 2009
- Adopting helical CT screening for lung cancerCancer, 2008
- Age-specific incidence of cancer: Phases, transitions, and biological implicationsProceedings of the National Academy of Sciences of the United States of America, 2008
- Lung Cancer Occurrence in Never-Smokers: An Analysis of 13 Cohorts and 22 Cancer Registry StudiesPLoS Medicine, 2008
- Estimating Long-term Effectiveness of Lung Cancer Screening in the Mayo CT Screening StudyRadiology, 2008
- Analysis of lung cancer incidence in the nurses’ health and the health professionals’ follow-up studies using a multistage carcinogenesis modelCancer Causes & Control, 2007
- How much of the decrease in cancer death rates in the United States is attributable to reductions in tobacco smoking?Tobacco Control, 2006
- Mortality in relation to smoking: 50 years' observations on male British doctorsBMJ, 2004
- Cigarette smoking and bronchial carcinoma: dose and time relationships among regular smokers and lifelong non-smokers.Journal of Epidemiology and Community Health, 1978