Irreversible Electroporation: A Novel Image-Guided Cancer Therapy
Open Access
- 1 September 2010
- journal article
- Published by The Editorial Office of Gut and Liver in Gut and Liver
- Vol. 4 (uppl.1), S99-S104
- https://doi.org/10.5009/gnl.2010.4.s1.s99
Abstract
Irreversible electroporation (IRE) is a novel tumor ablation technique using a non-thermal energy to create innumerable permanent nanopores in the cell membrane to disrupt cellular homeostasis. This disruption of cellular homeostasis initiates apoptosis which leads to permanent cell death. In our translational research, we have demonstrated that IRE can be a safe, fast and powerful method of tumor treatment. In this review, we present an overview of IRE ablation including a brief history of IRE, advantages and disadvantages of IRE and clinical and research implications of IRE.Keywords
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