Aripiprazole-induced tardive dyskinesia treated with quetiapine: a case report
- 1 August 2011
- journal article
- Published by Cambridge University Press (CUP) in Acta Neuropsychiatrica
- Vol. 23 (4), 188-190
- https://doi.org/10.1111/j.1601-5215.2011.00559.x
Abstract
Tomruk NB, Saatcioglu O, Yildizhan E, Alpay N. Aripiprazole-induced tardive dyskinesia treated with quetiapine: a case report.Background: Tardive dyskinesia (TD) is a serious, potentially irreversible side effect of antipsychotics. Although the risk is smaller, atypical antipsychotics still pose a risk. Aripiprazole is an atypical antipsychotic with a unique mechanism of action. It has a partial agonistic effect on the presynaptic D2 dopamine autoreceptor and antagonistic effect at postsynaptic D2 receptors.Method: There have been a few case reports of aripiprazole-induced TD. A case of aripiprazole-induced TD successfully treated with another atypical antipsychotic, quetiapine, is described and discussed in line with the recent literature.Results: TD showed rapid improvement with discontinuation of aripiprazole and initiation of quetiapine.Conclusion: Further studies are needed to ascertain the differential effects and side effects of second-generation antipsychotics in terms of TD.Keywords
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