Comparison of retinal thickness values and segmentation performance of different OCT devices in acute branch retinal vein occlusion
- 4 February 2011
- journal article
- Published by Springer Science and Business Media LLC in Eye
- Vol. 25 (4), 511-518
- https://doi.org/10.1038/eye.2010.216
Abstract
To compare retinal thickness (RT) measurement and segmentation performance of time domain (TD, Stratus) and spectral domain (SD) optical coherence tomography (OCT) devices (Cirrus, Spectralis) for imaging macular oedema (ME) secondary to branch retinal vein occlusion (BRVO). In this study, 20 eyes of 20 consecutive patients with acute BRVO were included. A total of 18 unaffected fellow eyes served as control group. RT measurement was analysed in the five inner fields of the early-treatment diabetic retinopathy grid, and proportional segmentation errors were evaluated. Central millimetre thickness (CMT) showed a mean difference of -64, -74, and -18 μm (P < 0.001) in the control group and -31 μm (P=0.107), -92 μm (P<0.001), and -105 μm (P=0.016) in the BRVO group, between Stratus and Cirrus, between Stratus and Spectralis, and between Cirrus and Spectralis, respectively. Mean RT showed the highest variability between different devices in the area most intensively affected by BRVO-related ME. In eyes with BRVO, 14.6% of Spectralis, 20% of Stratus, and 36.6% of Cirrus scans demonstrated moderate and severe segmentation errors. RT measurement in eyes with BRVO, by TD and SD OCT, is compromised by a significant rate of segmentation errors. Deviations are most pronounced in the areas most severely affected by ME.Keywords
This publication has 18 references indexed in Scilit:
- Spectral Domain Optical Coherence Tomography in Diabetic Macular EdemaOphthalmic Surgery, Lasers and Imaging Retina, 2009
- Three-dimensional Imaging of Cystoid Macular Edema in Retinal Vein OcclusionOphthalmology, 2008
- Intravitreal bevacizumab for the treatment of macular oedema secondary to branch retinal vein occlusionBritish Journal of Ophthalmology, 2008
- Branch Retinal Vein Occlusion: Pathogenesis, Visual Prognosis, and Treatment ModalitiesCurrent Eye Research, 2008
- Automatic segmentation in three-dimensional analysis of fibrovascular pigmentepithelial detachment using high-definition optical coherence tomographyBritish Journal of Ophthalmology, 2007
- Alignment Artifacts in Optical Coherence Tomography Analyzed ImagesOphthalmology, 2007
- Intravitreal Triamcinolone Acetonide for Patients with Macular Edema due to Branch Retinal Vein OcclusionThe Kaohsiung Journal of Medical Sciences, 2006
- Errors in Retinal Thickness Measurements Obtained by Optical Coherence TomographyOphthalmology, 2006
- Evaluation of image artifact produced by optical coherence tomography of retinal pathologyAmerican Journal of Ophthalmology, 2005
- Reproducibility of Nerve Fiber Thickness, Macular Thickness, and Optic Nerve Head Measurements Using StratusOCTPublished by Association for Research in Vision and Ophthalmology (ARVO) ,2004