The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability
Open Access
- 11 June 2013
- journal article
- Published by eLife Sciences Publications, Ltd in eLife
- Vol. 2, e00505
- https://doi.org/10.7554/elife.00505
Abstract
The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability | When a protein involved in DNA repair malfunctions, it can anneal RNA molecules to DNA molecules, creating hybrids that increase the frequency of mutations in the DNA.Keywords
Funding Information
- Howard Hughes Medical Institute
- Howard Hughes Medical Institute
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