Recent advances in the therapeutic applications of pyrazolines
- 8 March 2012
- journal article
- review article
- Published by Taylor & Francis Ltd in Expert Opinion on Therapeutic Patents
- Vol. 22 (3), 253-291
- https://doi.org/10.1517/13543776.2012.667403
Abstract
Introduction: Pyrazolines are well-known and important nitrogen-containing five-membered ring heterocyclic compounds. Various methods have been worked out for their synthesis. Several pyrazoline derivatives have been found to possess diverse biological properties, which has stimulated research activity in this field.Keywords
This publication has 97 references indexed in Scilit:
- Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma CellsCancer Research, 2011
- Synthesis, characterization, antiamoebic activity and cytotoxicity of novel series of pyrazoline derivatives bearing quinoline tailEuropean Journal of Medicinal Chemistry, 2010
- Synthesis, antitubercular activity and docking study of novel cyclic azole substituted diphenyl ether derivativesEuropean Journal of Medicinal Chemistry, 2009
- Extraction and determination of 2-pyrazoline derivatives using liquid phase microextraction based on solidification of floating organic dropJournal of Pharmaceutical and Biomedical Analysis, 2008
- Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some DipolarophilesMolecules, 2008
- Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestisBioorganic & Medicinal Chemistry Letters, 2008
- An improved synthesis of 1,3,5-triaryl-2-pyrazolines in acetic acid aqueous solution under ultrasound irradiationBeilstein Journal of Organic Chemistry, 2007
- Triaryl Pyrazoline Compound Inhibits Flavivirus RNA ReplicationAntimicrobial Agents and Chemotherapy, 2006
- 4,5-Dihydro-1H-pyrazole Derivatives with Inhibitory nNOS Activity in Rat Brain: Synthesis and Structure−Activity RelationshipsJournal of Medicinal Chemistry, 2004
- TGF-β induces apoptosis through Smad-mediated expression of DAP-kinaseNature, 2001