Critical validation of a new simpler approach to estimate aqueous pKa of drugs sparingly soluble in water
- 26 September 2005
- journal article
- Published by Elsevier BV in Analytica Chimica Acta
- Vol. 550 (1-2), 210-221
- https://doi.org/10.1016/j.aca.2005.06.058
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Spectrophotometric determination of acidity constants of 4-(2-pyridylazo)resorcinol in binary methanol–water mixturesAnalytica Chimica Acta, 2002
- Acidity in methanol–waterAnalytica Chimica Acta, 2001
- PH-metric logP 11. pKa determination of water-insoluble drugs in organic solvent–water mixturesJournal of Pharmaceutical and Biomedical Analysis, 1999
- Dissociation constants of neutral and charged acids in methyl alcohol. The acid strength resolutionAnalytica Chimica Acta, 1998
- Ionization constants of water insoluble arylpropionic acids in aqueous N,N-dimethylformamide mixtures from potentiometric pH-titrationsAnalytica Chimica Acta, 1997
- Dissociation constants of several non-steroidal anti-inflammatory drugs in isopropyl alcohol/water mixturesAnalytica Chimica Acta, 1997
- A comparison between different approaches to estimate the aqueous pKa values of several non-steroidal anti-inflammatory drugsAnalytica Chimica Acta, 1997
- Interlaboratory study of log {ce:inline-formula}P{/ce:inline-formula} determination by shake-flask and potentiometric methodsJournal of Pharmaceutical and Biomedical Analysis, 1996
- Determination of protonation macro- and microconstants and octanol/water partition coefficient of the antiinflammatory drug niflumic acidJournal of Pharmaceutical and Biomedical Analysis, 1994
- The liquid‐junction potentials between some buffer solutions in methanol and methanol‐water mixtures and a saturated KCl solution in water at 25°Recueil des Travaux Chimiques des Pays-Bas, 1960