Optical coherence tomography angiography in glaucoma
- 1 March 2019
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Current Opinion in Opthalmology
- Vol. 30 (2), 110-116
- https://doi.org/10.1097/icu.0000000000000554
Abstract
Optical coherence tomography angiography (OCTA) studies have demonstrated reduced microcirculation in the superficial optic nerve, peripapillary retina, and the macula of glaucoma patients. The scope of this review is to outline recent studies using OCTA in glaucoma and highlight how OCTA may help improve diagnosis and follow-up in glaucoma patients. OCTA studies have provided evidence of vascular changes in the optic nerve head, peripapillary, and macula region in glaucoma in comparison to glaucoma suspects and normal eyes. Additionally, OCTA can detect longitudinal reduction of peripapillary and macula vessel density in glaucoma patients. It remains unclear whether the reduced microcirculation in glaucoma patients induces the neuronal damage or arises through reduced circulation requirements in damaged tissue. OCTA is a novel imaging modality that has great potential to enhance our understanding of glaucoma and to improve our ability to detect and treat it.Keywords
This publication has 42 references indexed in Scilit:
- Peripapillary Retinal Nerve Fiber Layer Vascular Microcirculation in Eyes With Glaucoma and Single-Hemifield Visual Field LossJAMA Ophthalmology, 2017
- Peripapillary Retinal Nerve Fiber Layer Vascular Microcirculation in Glaucoma Using Optical Coherence Tomography–Based MicroangiographyInvestigative Ophthalmology & Visual Science, 2016
- Optic nerve head perfusion in normal eyes and eyes with glaucoma using optical coherence tomography-based microangiographyQuantitative Imaging in Medicine and Surgery, 2016
- Optical Coherence Tomography Angiography of the Peripapillary Retina in GlaucomaJAMA Ophthalmology, 2015
- Optical Coherence Tomography Angiography of Optic Disc Perfusion in GlaucomaOphthalmology, 2014
- Split-spectrum amplitude-decorrelation angiography with optical coherence tomographyOptics Express, 2012
- The number of people with glaucoma worldwide in 2010 and 2020British Journal of Ophthalmology, 2006
- The impact of ocular blood flow in glaucomaProgress in Retinal and Eye Research, 2002
- Optic nerve blood-flow abnormalities in glaucomaProgress in Retinal and Eye Research, 1998
- Relationship Between Intraocular Pressure and Primary Open Angle Glaucoma Among White and Black AmericansAmerican Journal of Ophthalmology, 1991